Medel för att söva patienter med covid-19 tar snart slut
I Stockholm råder stor brist på läkemedlet Propofol, som används för att söva patienter med covid-19 när de andas med hjälp av respirator. Det rapporterar SVT Nyheter med hänvisning till interna mejl i regionen.
I ett mejl till ett av stadens större sjukhus uppmanas personalen att använda narkosmedlet Pento i stället, trots att det innebär större risker för patienterna.
Gerd Lärfars, enhetschef på hälso- och sjukvårdsförvaltningen, säger att man nu ligger på läkemedelstillverkare för att de ska öka produktionen av Propofol.
bakgrund
Propofol
Wikipedia (en)
Propofol, marketed as Diprivan among other names, is a short-acting medication that results in a decreased level of consciousness and lack of memory for events. Its uses include the starting and maintenance of general anesthesia, sedation for mechanically ventilated adults, and procedural sedation. It is also used for status epilepticus if other medications have not worked. It is given by injection into a vein. Maximum effect takes about two minutes to occur and it typically lasts five to ten minutes.Common side effects include an irregular heart rate, low blood pressure, burning sensation at the site of injection, and the stopping of breathing. Other serious side effects may include seizures, infections with improper use, addiction, and propofol infusion syndrome with long-term use. It appears to be safe for using during pregnancy but has not been well studied in this group. However, it is not recommended during cesarean section. Propofol is not a pain medication, so opioids such as morphine may also be used. Whether or not they are always needed is unclear. Propofol is believed to work at least partly via a receptor for GABA.Propofol was discovered in 1977 and approved for use in the United States in 1989. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. It is available as a generic medication. The wholesale price in the developing world is between 0.61 and 8.50 USD per vial. It has been referred to as milk of amnesia (a play on milk of magnesia) because of the milk-like appearance of the intravenous preparation. Propofol is also used in veterinary medicine for anesthesia.
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